The Impact of Monitoring Techniques on Progression to Chronic Breast Cancer-related Lymphedema

Chirag Shah, MD, April Zambelli-Weiner, Nicole Delgado, Ashley Sier, Robert Bauserman, Jerrod Nelms

This meta‑analysis comparing bioimpedance spectroscopy versus circumferential measurement includes:

  • 50 lymphedema studies and over 67,000 patients studied
  • Investigated BCRL in breast cancer patients
  • Analyzed impact of prospective monitoring and intervention
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3-Key Takeaways from Meta-Analysis Comparing Bioimpedance Spectroscopy vs. Circumferential Measurement

81% Lower Rate of Chronic Lymphedema than Circumference Monitoring

81% Lower Rate of Chronic Lymphedema than Circumference Monitoring

This recent meta-analysis confirms that routine monitoring for early detection of lymphedema using ImpediMed’s L-Dex® technology, combined with early intervention, cuts the relative rate of chronic breast cancer-related lymphedema by 81% when compared to circumference monitoring.

Statistically Lower Rates of Chronic Lymphedema in High-Risk Patients and Short-Term and Long-Term Follow-up

Statistically Lower Rates of Chronic Lymphedema in High-Risk Patients and Short-Term and Long-Term Follow-up

The benefit is sustained in high-risk subgroups as well as short-term and long-term follow-up. L-Dex monitoring and intervention studies showed a statistically significant reduction in chronic lymphedema in studies with >50% axillary lymph node dissection (ALND), >40% mastectomy, <2 years follow-up, and >2 years follow-up when compared to circumference studies.

Statistically Lower Rates of Chronic Lymphedema in High-Risk Patients and Short-Term and Long-Term Follow-up

Statistically Lower Rates of Chronic Lymphedema in High-Risk Patients and Short-Term and Long-Term Follow-up

The benefit is sustained in high-risk subgroups as well as short-term and long-term follow-up. L-Dex monitoring and intervention studies showed a statistically significant reduction in chronic lymphedema in studies with >50% axillary lymph node dissection (ALND), >40% mastectomy, <2 years follow-up, and >2 years follow-up when compared to circumference studies.

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