More Sensitive than Weight Alone
Differentiates between fluid and tissue-related weight changes.
Heart failure (HF), also known as congestive heart failure or chronic heart failure (CHF), affects ~26 million people globally. Current monitoring technologies such as weight scales or implantable pulmonary artery pressure (PAP) monitors are either inaccurate or require invasive procedures. SOZO offers a fast, accurate, and non-invasive measurement of fluid burden to better monitor and manage heart failure patients.
Our goal is to improve quality of life and reduce readmissions of heart failure patients.
Reduced cardiac function in heart failure patients leads to a buildup of extracellular fluid. The extent of volume overload leading to decompensation, and symptoms that drive hospitalization, can vary from patient to patient and change with disease progression.
The HF-Dex heart failure index provides a consistent metric for tracking fluid volumes and changes due to impaired cardiac function or medication. A HF-Dex over 51% is a marker for potential future hospital readmission in heart failure patients.
Measure patients with SOZO during routine office visits to help assess volume status and to determine whether to adjust medications/therapy for the purpose of managing patient fluid status, symptoms, and condition.
Measure patients with SOZO in the hospital to help determine whether a patient is high risk for readmission prior to discharge in order to extend hospital stay or alter discharge instructions.
Measure patients with SOZO upon hospital admission to help determine whether a patient’s symptoms result from fluid status in order to prioritize treatments based on the severity of their condition.
Measure patients with SOZO at home to help assess volume status and to determine whether to adjust medications/therapy for the purpose of managing patient fluid status, symptoms, and condition.
1. Savarese, G. and L.H. Lund, Global Public Health Burden of Heart Failure. Card Fail Rev, 2017. 3(1): p. 7-11.
2. Dharmarajan, K., et al., Diagnoses and timing of 30-day readmissions after hospitalization for heart failure, acute myocardial infarction, or pneumonia. JAMA 2013. 309(4): p. 355-63.
3. Desai, A.S. and L.W. Stevenson, Rehospitalization for heart failure: predict or prevent? Circulation, 2012. 126(4): p. 501-6.
4. Peled H. Letter to the editor: readmissions and diuretic dosing. JACC Heart Failure 2017;5(8)618 9.
5. Serra-Prat M, et al. Intracellular Water Content in Lean Mass is Associated with Muscle Strength, Functional Capacity, and Frailty in Community-Dwelling Elderly Individuals. A Cross-Sectional Study. Nutrients 2019;doi:10.3390/nu11030661.
6. Serra-Prat M, et al. Intracellular Water Content in Lean Mass is Associated with Muscle Strength, Functional Capacity, and Frailty in Community-Dwelling Elderly Individuals. A Cross-Sectional Study. Nutrients 2019;doi:10.3390/nu11030661.
7. Serra-Prat M, et al. Total Body Water and Intracellular Water Relationships With Muscle Strength, Frailty and Functional Performance in an Elderly Population. J Nutr Health Aging . 2019;23(1):96-101.
8. Capillary Fluid Exchange: Regulation, Functions, and Pathology. Scallan J, Huxley VH, Korthuis RJ. San Rafael (CA): Morgan & Claypool Life Sciences; 2010.
9. Kimura G, et al. A simulation study on transcellular fluid shifts induced by hemodialysis. Kidney International. 1983;24:542-8.