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Patient Data

HF-DEX® ANALYSIS

Know your Patients Risk of Readmission in 30 Seconds

Fluid may change long before symptoms or significant weight change. HF-Dex® gives you the clarity to see them early—so you can intervene sooner and keep patients out of the hospital.

Backed by Evidence

  • If HF-Dex is >51% a patient is four times more likely to be readmitted compared to weight monitoring alone1
  • 30-second test with real time results in a non-invasive, easy to use and repeatable point of care solution
  • The SOZO Digital Health Platform is an FDA-cleared solution that has two times greater sensitivity compared to weight in daily monitoring2
  • 93701 CPT Code with Medicare national coverage
HF-DEX ANALYSIS OUTPUT

Extracellular Fluid (ECF) Changes Reveal What Weight Cannot

Patients may feel better or worse before their weight changes. ECF provides a clearer picture of what’s happening physiologically—allowing earlier intervention to keep patients stable and out of the hospital.

Extracellular Fluid (ECF) Changes Reveal What Weight Cannot

CASE STUDY

Managing Heart Patients with more
Accurate Data Outside of the Hospital

Case Study

Seeing What Traditional Monitoring Missed After Discharge with HF-Dex. This 87-year-old male with NYHA II–III heart failure was monitored. Despite periods of clinical stability, HF-Dex remained elevated (>51%) for nearly 100 days, aligning with two subsequent readmissions.

What the Clinician Saw

  1. HF-Dex stayed above 51% for ~100 days, signaling persistent congestion and aligning with both readmissions.
  2. Weight remained largely unchanged during periods when HF-Dex indicated elevated risk—showing weight alone missed clinical deterioration.
  3. ECF shifted meaningfully even when weight changed <1 kg, reflecting true fluid dynamics and matching symptom patterns.

Tablet screen with medical data

After the patient was treated, HF-Dex dropped toward ~50.3% and ECF toward 16.3 L, confirming effective decongestion despite minimal weight change.

Observation from Heart Failure at Home study; clinicians and patients were blinded to BIS data during follow-up.

CONNECTED CARE SOLUTIONS

Clinically Validated Technology

Precision care starts with precision measurement. SOZO provides actionable insights for fluid and body composition management — at the bedside, clinic, or rehab.

HF-Dex for Volume Optimization

HF-Dex has 80% sensitivity and specificity for distinguishing fluid status in patients. Clear triggers, HF-Dex is 46.4% to 51% conduct further clinical investigation.3

Learn More

Body Composition for Holistic Patient Care

SOZO BodyComp™ Analysis measures skeletal muscle mass and fat mass, at 256 frequencies for obesity and cardiac rehab care.

Learn More
Contact us to learn more about SOZO with HF-Dex
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References

  1. Daleiden-Burns A, Accardi A and Heywood JT. Bioimpedance Spectroscopy Measurement of Ongoing Fluid Overload Post-Discharge from Hospitalization for Decompensated Heart Failure. JACC.2021 May 11; 77(18):798
  2. Daleiden-Burns A, Accardi A and Heywood JT. Time-to-Decongestion Following Heart Failure Hospitalization as Measured by Extracellular Fluid Nadir Using Bioimpedance Spectroscopy. Journal of Cardiac Failure, Volume 28, Issue 5, S15
  3. Anne Daleiden-Burns, Andrew Accardi, Tishangi Kumar, Luay Sarsam, J. Thomas Heywood, Bioimpedance Spectroscopy Distinguishes Between Fluid Status In Individuals With And Without Heart Failure, Journal of Cardiac Failure, Volume 29, Issue 4, 2023, Pages 656-657. doi: 10.1016/j.cardfail.2022.10.269