Lymphedema is one of the most feared consequences of cancer treatment among survivors. Early detection is critical to preventing lymphedema from becoming a chronic condition. SOZO® with L-Dex® helps healthcare professionals to identify at-risk patients early and intervene before lymphedema becomes irreversible.

Early detection of secondary lymphedema using L-Dex combined with at-home intervention using standard compression therapy has been shown reduce the progression of lymphedema by 95%1.

Fluid Analysis for Lymphedema

The SOZO Digital Health Platform provides the L-Dex score to measure and assess fluid buildup in an at-risk limb and help detect early signs of lymphedema. It uses noninvasive bioimpedance spectroscopy (BIS), which is capable of detecting fluid changes as small as 2.4 tablespoons (36ml) and takes less than 30 seconds to complete2.


Lymphedema Prevention Program

ImpediMed’s Test, Trigger, Treat™ protocol for lymphedema prevention.

81% Lower Rate of Chronic Lymphedema than Circumference Monitoring

NEW DATA! ImpediMed’s L-Dex® technology versus circumferential monitoring

Reimbursement Services

Understand U.S. reimbursement for using SOZO with L-Dex for lymphedema assessment.

Cancer-Related Lymphedema

Secondary lymphedema is a leading post-treatment complication for many cancer patients, costing the U.S. healthcare system an estimated $7 billion annually.3 Of the nearly 17 million cancer survivors in the U.S., roughly one in three treated for the cancers below will develop chronic lymphedema.4,5

Lymphedema is a risk for women and men treated with surgery, radiation or Taxane-based chemotherapy for multiple cancer types, including:

Breast Cancer,  Melanoma,  Pelvic area cancers

Preventing Cancer-Related Lymphedema

In the past, the onset of lymphedema was too difficult to detect using standard measurement techniques. Now, SOZO with L-Dex technology aids in detecting lymphedema at the subclinical level, or Stage 0, before visible swelling and the condition is irreversible. By the time patients experience lymphedema symptoms, it may be too late to reverse the condition.

Early detection of lymphedema at the subclinical level before any swelling is visible is critical. SOZO with L-Dex delivers a precise snapshot of fluid status in less than 30 seconds2. Early detection of fluid accumulation coupled with standard, at-home compression treatment has been shown to reduce lymphedema progression by 95%1.


Clinical Practice Guidelines

Early detection and treatment of lymphedema to improve patient outcomes is recommended in multiple clinical practice guidelines, including:

· American Physical Therapy Association

· eviCore Clinical Guidelines for Physical and occupational Therapy Service

· Lymphatic Education & Research Network (LE&RN) Centers of Excellence

· National Accreditation Program for Breast Centers (NAPBC)

· National Comprehensive Cancer Network (NCCN) Guidelines for Breast Cancer

· National Lymphedema Network

See Who Is Using SOZO for Lymphedema

SOZO is used at leading cancer institutions to aid in the early detection of lymphedema.



ImpediMed is proud to partner with LIVE Today Foundation and Lymphatic Research & Education Network to grow awareness for lymphatic diseases and their impact on patients and to improve access to care.

LIVE Today Foundation

LIVE Today was founded by Dr. Sheri Prentiss to provide free compression garments to underserved patients and survivors with lymphedema. Dr. Sheri is an occupational and environmental medicine physician, public health expert, breast cancer survivor, and lymphedema patient. Her Foundation works to educate patients and healthcare practitioners about lymphedema and provide access to compression garments.

Lymphatic Education & Research Network

The Lymphatic Education & Research Network (LE&RN) Education supports education, research, and advocacy for patients living with lymphatic diseases. Since its founding in 1998, LE&RN has made great strides in lymphatic disease advocacy, including securing ongoing Congressional and National Institutes of Health (NIH) support for lymphatic research and lymphatic diseases. LE&RN also launched the Centers of Excellence Program to increase access to clinical care and services for patients and their families.


ImpediMed is here to support you in implementing a Lymphedema Prevention Program for your cancer patients.

Patient Education,  Training and Implementation,  Reimbursement

Training Resources

Contact Us

Contact us to learn more about SOZO with L-Dex and the benefits of implementing a Lymphedema Prevention Program for your cancer patients.

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  1. Ridner SH, et al. A randomized trial evaluating bioimpedance spectroscopy versus tape measurement for the prevention of lymphedema following treatment for breast cancer: interim analysis. Ann Surg Oncol 2019;
  2. As tested on Android.
  3. ImpediMed estimate.
  4. National Cancer Institute website: Accessed April 30, 2019.
  5. Shaitelman SF, et al. Recent Progress in the Treatment and Prevention of Cancer-Related Lymphedema. CA Cancer J Clin 2015;65:55-81.